Syntic Life is advancing multiple investigational programs that target the biology of aging across different organ systems. Each works upstream of disease, at the level of the processes that drive how tissues age. Programs progress through clearly defined, independently validated stages, advancing only on reproducible results that meet predefined criteria. All programs are preclinical; none has entered clinical development, and our therapies remain investigational and not approved by any regulatory authority.
Discovery
Identifying and prioritizing the biological targets and candidate approaches that anchor a program.
Cellular Validation
Testing those candidates in human and other cell models to confirm the intended biological effect.
In Vivo (Rodent)
Evaluating efficacy, durability, and safety signals in living animal models.
IND-Enabling Studies
Conducting the formal safety, biodistribution, and manufacturing work required before clinical testing can be proposed.
Targeting the epigenetic and transcriptional regulators that drive cellular aging, with the goal of restoring aged cells toward a younger, healthier state.
Status: Positive results to date; advancing toward IND-enabling studies.
Discovery
Cellular Validation
In Vivo (Rodent)
IND-Enabling Studies
Investigating the pathways that govern glucose metabolism, lipid regulation, and energy balance, which decline with age and underlie many chronic metabolic conditions.
Discovery
Cellular Validation
In Vivo (Rodent)
IND-Enabling Studies
Exploring the protein systems linked to synaptic function, neuroinflammation, and neuronal resilience that help preserve cognitive function over time.
Discovery
Cellular Validation
In Vivo (Rodent)
IND-Enabling Studies
Studying the pathways involved in muscle maintenance, regeneration, and tissue strength, with the goal of countering age-related loss of mobility and function.
Discovery
Cellular Validation
In Vivo (Rodent)
IND-Enabling Studies
All programs are in preclinical, investigational stages. Results were obtained in laboratory and animal models and do not predict outcomes in humans.
Syntic Life's technologies are in preclinical development and are not approved for human use. Results described were obtained in laboratory and animal models and do not predict outcomes in humans. All research is conducted in compliance with applicable institutional, ethical, and regulatory standards. Statements regarding our research, pipeline, and vision are forward-looking and reflect current scientific hypotheses, not clinical outcomes or regulatory approvals.
